Hudson was born in Benton Harbor, Michigan, the son of Maggie Donald, who died of tuberculosis when Hudson was two months old; Hudson never knew his father. He was subsequently raised by his maternal grandmother, Arrana Donald. He became a resident playwright at Concept East, and later enrolled at Wayne State University to develop his acting and writing skills.
One of Hudson's early films was in Penitentiary in the late 1970s starring Leon Isaac Kennedy. After appearing on many television shows, he went on to star in Ghostbusters as well as it's sequel.
- The A-Team
- Ghostbuster II
- Miss Congeniality
- Desperate Housewives